- B6 (See other available formats)
- Regulatory Status
- Other Names
- T cell receptor V δ 2
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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The Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.Product Details
- Human, Cross-Reactivity: Chimpanzee, Rhesus
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Becton, Dickinson and Company and its affiliates. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. patent(s), pending patent applications and/or foreign equivalents.
- Excitation Laser
Violet Laser (405 nm)
- Application References
- Rojas RE, et al. 2005. J. Infect. Dis. 192:1806.
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
AB_2783212 (BioLegend Cat. No. 331429)
AB_2783213 (BioLegend Cat. No. 331430)
- Ig superfamily member, TCR γ/δ with CD3 forms the CD3/TCR complex
Expressed on majority of peripheral γ/δT cells
- Antigen recognition, T cell activation
- Peptide bound to MHC
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- Antigen References
1. Scotet E, et al. 2005. Immunity 22:71.
2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144.
- Gene ID
- 6964 View all products for this Gene ID
- View information about TCR Vdelta2 on UniProt.org
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