Purified anti-mouse CD170 (Siglec-F) Recombinant Antibody

Pricing & Availability
Clone
QA20A11 (See other available formats)
Regulatory Status
RUO
Other Names
OBBP2, CD33L2, OB-BP2
Isotype
Rat IgG1, κ
Ave. Rating
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Product Citations
publications
QA20A11_PURE_CD170_Antibody_012022_updated
C57BL/6 mouse splenocytes were stained with purified anti-mouse CD170 (Siglec-F) recombinant (clone QA20A11) (left) or purified rat IgG1, κ isotype control (right), followed by anti-rat IgG PE. Cells were then stained with anti-mouse CD193 (CCR3) APC.
  • QA20A11_PURE_CD170_Antibody_012022_updated
    C57BL/6 mouse splenocytes were stained with purified anti-mouse CD170 (Siglec-F) recombinant (clone QA20A11) (left) or purified rat IgG1, κ isotype control (right), followed by anti-rat IgG PE. Cells were then stained with anti-mouse CD193 (CCR3) APC.
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164102 100 µg £215
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Description

CD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and 2 ITIM motifs in the cytoplasmic domain; preferentially binds [alpha]-2,3-linked sialic acid. Siglec F is expressed in eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of the lung eosinophils during allergic asthma.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Recombinant
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This recombinant antibody clone is derived from clone S17007L.

RRID
AB_2922500 (BioLegend Cat. No. 164102)

Antigen Details

Structure
Member of the immunoglobulin superfamily, single pass transmembrane protein, forms a 140 kD dimer; cytoplasmic domain contains two ITIM motifs
Distribution

Granulocytes, Monocytes, Macrophages, Lymphocytes, Dendritic cells, B cells, eosinophils.

Function
Inhibitory receptor, cell adhesion
Ligand/Receptor
α2,3- and α2,6-linked sialic acid.
Gene ID
8778 View all products for this Gene ID
UniProt
View information about CD170 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 01/19/2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • PE anti-mouse CD170 Recombinant Antibody

  • Purified anti-mouse CD170 (Siglec-F) Recombinant Antibody

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