Purified anti-human CD177 Antibody

Pricing & Availability
MEM-166 (See other available formats)
Regulatory Status
HCDM listed
Other Names
Neutrophil specific antigen 1, NB1, polycythemia rubra vera 1
Mouse IgG1, κ
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Product Citations
Human peripheral blood granulocytes stained with purified MEM-166, followed by anti-mouse IgG FITC
  • MEM-166_Pure_020708
    Human peripheral blood granulocytes stained with purified MEM-166, followed by anti-mouse IgG FITC
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315802 100 µg £65.00
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CD177 is also known as neutrophil specific antigen 1, NB1, and polycythemia rubra vera 1. It is a member of the uPAR family and is a GPI-linked cell surface glycoprotein with a molecular weight of 60 kD. CD177 is expressed on granulocytes and bone marrow progenitors (early erythroblasts, megakaryocytes). It is thought to be involved in allogeneic and autoimmune responses to neutrophils.

Product Details
Technical Data Sheet (pdf)

Product Details

Human, Cross-Reactivity: Rhesus
Antibody Type
Host Species
Human granulocytes
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
ICC, IP, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting5, and immunofluorescence4.

Application References

(PubMed link indicates BioLegend citation)
  1. Leucocyte Typing VII. Mason D, et al. Eds, 2002 Oxford University Press.
  2. von Vietinghoff S, et al. 2007. Blood 109:4487. PubMed
  3. Korkmaz B, et al. 2008. J. Biol. Chem. 283:35976. PubMed
  4. von Vietinghoff S, et al. 2007. Blood 109:4487. (IF)
  5. Jankowska AM, et al. 2011. Haematologica. 96:954. (WB)
Product Citations
  1. Vietinghoff S, et al. 2007. Blood. 109:4487. PubMed
  2. Korkmaz B, et al. 2008. J Biol Chem. 283:35976. PubMed
AB_2072605 (BioLegend Cat. No. 315802)

Antigen Details

uPAR family, GPI-linked cell surface glycoprotein, 60 kD

Granulocytes, bone marrow progenitors (early erythroblasts, megakaryocytes)

Antigen involved in neutrophil allo- and autoimmunity, function unknown
Cell Type
Granulocytes, Hematopoietic stem and progenitors, Neutrophils
Biology Area
Molecular Family
CD Molecules
Antigen References

1. Leukocyte Typing VII. Mason D, et al. (Eds.) Oxford University Press (2002)
2. Kissel K, et al. 2001. Eur. J. Immunol. 31:1301.
3. Lalezari P, et al. 1971. J. Clin. Invest. 50:1108.
4. Temerinac S, et al. 2000. Blood 95:2569.

Gene ID
57126 View all products for this Gene ID
View information about CD177 on UniProt.org

Related FAQs

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Go To Top Version: 4    Revision Date: 01/19/2021

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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