Purified anti-human CD132 (common γ chain) Recombinant Antibody

Pricing & Availability
Clone
QA17A55 (See other available formats)
Regulatory Status
RUO
Other Names
Common γ chain, γc, IL-2 receptor γ subunit
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA17A55_PURE_CD132_Antibody_051721
Human peripheral blood lymphocytes were stained with CD132 (clone QA17A55) purified (filled histogram) or mouse IgG1, κ purified isotype control (open histogram) followed by goat anti-mouse IgG Biotin and Streptavidin-PE
  • QA17A55_PURE_CD132_Antibody_051721
    Human peripheral blood lymphocytes were stained with CD132 (clone QA17A55) purified (filled histogram) or mouse IgG1, κ purified isotype control (open histogram) followed by goat anti-mouse IgG Biotin and Streptavidin-PE
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314602 100 µg £85
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Description

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2892384 (BioLegend Cat. No. 314602)

Antigen Details

Structure
Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
Distribution

T cells, B cells, NK, monocytes, granulocytes

Ligand/Receptor
Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
Antigen References

1. Corrigall V, et al. 2001. J Immunol. 166(6):4141-7.

Gene ID
3561 View all products for this Gene ID
UniProt
View information about CD132 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 04/12/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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