PE anti-mouse Granzyme A Antibody

Pricing & Availability
3G8.5 (See other available formats)
Regulatory Status
Other Names
Hf, SE1, TSP1, Ctla3, TSP-1, Ctla-3, AW494114
Mouse IgG2b, κ
Ave. Rating
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Product Citations
CD3/CD28 (three days) stimulated BALB/c splenocytes were intracellularly stained with CD8 APC and granzyme A (clone 3G8.5) PE (top) or mouse IgG2b, κ PE isotype control (bottom).
  • 3G8.5_PE_GranzymeA_Antibody_ICFC_1_022415
    CD3/CD28 (three days) stimulated BALB/c splenocytes were intracellularly stained with CD8 APC and granzyme A (clone 3G8.5) PE (top) or mouse IgG2b, κ PE isotype control (bottom).
  • 3G8.5_PE_GranzymeA_Antibody_ICFC_2_022415
See PE spectral data
Cat # Size Price Save
149703 25 µg ¥25,000
149704 100 µg ¥57,000

Granzyme A is a serine protease that is similar to Granzyme B. However, unlike granzyme B, granzyme A is a homodimer. It is expressed in cytotoxic T cells and natural killer cells (NK), but is not essential for induction of apoptosis or DNA fragmentation. Cell death induced by granzyme A is slower and morphologically different than the cell death induced by granzyme B. It plays a crucial role in infection-mediated inflammation as well as immunological responses against viruses, bacteria, and tumor cells.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Full length recombinant granzyme A of mouse origin.
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Fehniger TA, et al. 2007. Immunity 26:798. (ICFC)
Product Citations
  1. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  2. Findlay EG, et al. 2019. Oncoimmunology. 8:1608106. PubMed
  3. Thom SR, et al. 2017. J Appl Physiol (1985). 123:297. PubMed
  4. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  5. Wiedemann GM, et al. 2020. Cell Rep. 33:108498. PubMed
  6. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
AB_2565309 (BioLegend Cat. No. 149703)
AB_2565310 (BioLegend Cat. No. 149704)

Antigen Details

29 kD, Homodimer, Serine protease

Cytotoxic T cells and natural killer cells (NK); low on granulocytes, B cells, and activated dendritic cells (DCs).

Induction of cell death and apoptosis.
Cell Type
T cells, NK cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroscience
Molecular Family
Proteases, Enzymes and Regulators
Antigen References

1. Susanto O, et al. 2013. Cell Death Differ. 20:1183.
2. Ebnet K, et al. 1995. EMBO J. 14:4230.
3. Jenne DE, et al. 1988. Immunol. Rev. 103:53.

Gene ID
14938 View all products for this Gene ID
View information about Granzyme A on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 02/24/2015

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse Granzyme A

  • PE anti-mouse Granzyme A

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