- 11C3.1 (See other available formats)
- Other Names
- Gp34, OX40L, CD134L, CD252, TNFSF4
- Mouse IgG1, κ
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- Product Citations
OX40 ligand (OX40L) is a 35 kD type II transmembrane protein which belongs to TNF superfamily, also known as gp34, CD252, CD134L or TNFSF4. The OX40 ligand is expressed on activated B cells, activated endothelial cells, mature dendritic cells, activated CTLs, activated mast cells, and airway smooth muscle cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to regulate T cell proliferation and differentiation, and to enhance immunoglobulin secretion by activated B cells.Product Details
- Human, African Green Monkey
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2303694 (BioLegend Cat. No. 326306)
- NGF/TNF superfamily, 35 kD
Activated B cells, activated endothelial cells, mature dendritic cells, airway smooth muscle cells
- B-cell/T-cell interaction, costimulation
- OX40 (CD134)
- Cell Type
- B cells, Endothelial cells, Dendritic cells
- Biology Area
- Immunology, Costimulatory Molecules
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
1. Imura A, et al. 1996. J. Exp. Med. 183:2185.
2. Ohshima Y, et al. 1997. J. Immunol. 159:3838.
3. Ito T, et al. 2005. J. Exp.Med. 202:1213.
4. Ito T, et al. 2006. Proc. Natl. Acad.Sci. USA. 103:13138.
- Gene ID
- 7292 View all products for this Gene ID
- View information about CD252 on UniProt.org
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
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