- 17A2 (See other available formats)
- Regulatory Status
- Other Names
- T cell antigen receptor complex, T3
- Rat IgG2b, κ
- Ave. Rating
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- Product Citations
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CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complexProduct Details
- Antibody Type
- Host Species
- γδTCR-positive T-T hybridoma D1
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.
- Product Citations
AB_2572117 (BioLegend Cat. No. 100247)
AB_2572118 (BioLegend Cat. No. 100248)
- Ig superfamily, CD3/TCR, 20 kD
Thymocytes (differentiation dependent), mature T cells, NK-T cells
- Antigen recognition, TCR signal transduction, T cell activation
- Peptide antigen/MHC-complex
- Antigen References
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.
- Gene ID
- 12502 View all products for this Gene ID
- View information about CD3 on UniProt.org
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