- Clone
- W17055E (See other available formats)
- Other Names
- Human TGF-b Receptor II, TGFbRII
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with CD3 APC/Cyanine7 and TGF-β receptor II (clone W17055E) APC or rat IgG2b, κ APC isotype control.
| Cat # | Size | Price | Quantity Avail. | Save | ||
|---|---|---|---|---|---|---|
| 399705 | 25 tests | 232€ | ||||
| 399706 | 100 tests | 472€ | ||||
Transforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- TGFbR2 protein (aa 1-243) expressing transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_2876726 (BioLegend Cat. No. 399705)
Antigen Details
- Distribution
-
B cells, T cells, monocytes, and granulocytes.
- Ligand/Receptor
- TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.
- Cell Type
- B cells, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
- Horbelt D, et al. 2010. J Cell Sci. 123:4340-50.
- Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29.
- Numata S, et al. 2008. J Psychiatr Res. 42:425-32.
- Gene ID
- 7048 View all products for this Gene ID
- UniProt
- View information about TGF-beta Receptor II on UniProt.org
Related Pages & Pathways
Pathways
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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