Loading...

FITC anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_FITC_1_110210
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) FITC (top) or rat IgG2b, κ FITC isotype control (bottom) (gated on total viable cells).
  • M1slash70_FITC_1_110210
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) FITC (top) or rat IgG2b, κ FITC isotype control (bottom) (gated on total viable cells).
  • M1slash70_FITC_2_110210
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
101205 50 µg 38€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101206 500 µg 106€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Gupta P, Rajan M, Kulkarni S, et al. 2017. Int Immunopharmacol. 10.1016/j.intimp.2017.06.025. PubMed
  2. Haimon Z et al. 2018. Nature immunology. 19(6):636-644 . PubMed
  3. Bijland S, et al. 2019. F1000Res. 8:117. PubMed
  4. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  5. Miyatake Y, et al. 2018. J Immunol. 201:3051. PubMed
  6. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  7. Petrova T, et al. 2020. Sci Rep. 10:3479. PubMed
  8. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  9. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  10. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  11. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  12. Schädlich IS, et al. 2022. iScience. 25:104470. PubMed
  13. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  14. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  15. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  16. Narusawa M, et al. 2014. Cancer Immunol Res. 2:568. PubMed
  17. Ostapoff K, et al. 2014. Cancer Res. 74:4966. PubMed
  18. Fan X, et al. 2015. Cancer Res. 75:86. PubMed
  19. Wang L, et al. 2020. Front Cell Dev Biol. 0.745138889. PubMed
  20. Moreno-García Á, et al. 2020. Biomolecules. 10:00. PubMed
  21. Xue F, et al. 2020. Int J Biol Sci. 2.105555556. PubMed
  22. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  23. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  24. Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
  25. Liu W, et al. 2020. Mol Ther Oncolytics. 17:350. PubMed
  26. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  27. Bo Yu et al. 2018. Cell stem cell. 23(2):193-209 . PubMed
  28. Shavit Stein E, et al. 2018. Neural Plast. 2018:7692182. PubMed
  29. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  30. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  31. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  32. Gan C, et al. 2022. Respir Res. 23:32. PubMed
  33. He J, et al. 2022. Front Immunol. 12:760138. PubMed
  34. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  35. Okajima T, et al. 2021. Front Immunol. 12:738041. PubMed
  36. Pathak JL, et al. 2021. Front Cell Dev Biol. 628139:9. PubMed
  37. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  38. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  39. Rosenkranz SC, et al. 2021. eLife. 10:00. PubMed
  40. Han X, et al. 2017. Int J Mol Sci. 10.3390/ijms18050942. PubMed
  41. Belmonte L, et al. 2016. Sci Rep. 6:35813. PubMed
  42. Nocera D, et al. 2016. J Immunol. 196: 2860 - 2869. PubMed
  43. Jackson A, et al. 2014. J Leukoc Biol. 92:609. PubMed
  44. Zhang Y, et al. 2018. Sci Rep. 8:5994. PubMed
  45. Zhang YS, et al. 2018. Cancer Biol Ther. 19:735. PubMed
  46. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  47. Wu G, et al. 2020. Front Oncol. 10:194. PubMed
  48. Lee H, et al. 2020. Cell Metabolism. 31(4):822-836. PubMed
  49. Lin R, et al. 2020. Sci Rep. 10:14397. PubMed
  50. Koning B, et al. 2006. Int Immunol. 1.403472222. PubMed
  51. Kapadia D, et al. 2011. PLoS One. 6:e19376. PubMed
  52. Pandey S, et al. 2020. Cell Syst. 11:495. PubMed
  53. Tuominen S, et al. 2021. Eur J Nucl Med Mol Imaging. 48:1312. PubMed
  54. Li Y, et al. 2021. Basic Res Cardiol. 116:30. PubMed
  55. Poli V, et al. 2021. iScience. 24:103256. PubMed
  56. Xu ZH, et al. 2021. Mediators Inflamm. 2021:8856326. PubMed
  57. Choi YY, et al. 2021. Cell Death Dis. 12:826. PubMed
  58. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  59. Zhu ZY, et al. 2022. Front Immunol. 12:781087. PubMed
  60. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  61. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  62. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  63. Hu J, et al. 2021. Sci Adv. 7:. PubMed
  64. Chen S, et al. 2022. Cancer Discov. :. PubMed
  65. Patel T, et al. 2022. Aging Cell. 21:e13606. PubMed
  66. Paschall A, et al. 2015. J Immunol. 194: 2369-2379. PubMed
  67. Su N, Xiong Y 2016. Sci Rep. 6:22658. PubMed
  68. Tu S, et al. 2020. Cellular Signalling. 73:109695. PubMed
  69. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  70. Zaytseva D, et al. 2018. Physiol Rep. 6:e13812. PubMed
  71. Tong X, et al. 2020. Front Pharmacol. 1.404166667. PubMed
  72. Shang W, et al. 2019. J Diabetes Res. 2019:5641271. PubMed
  73. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  74. Lindborg JA et al. 2017. The Journal of Neuroscience. 37(43):10258-10277 . PubMed
  75. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  76. Duan M, et al. 2022. Cell Commun Signal. 20:60. PubMed
  77. Zhang Q, et al. 2021. Theranostics. 11:8301. PubMed
  78. Li B, et al. 2022. iScience. 25:103772. PubMed
  79. DeMarco JK, et al. 2021. Vaccines (Basel). 9:. PubMed
  80. Klichinsky M, et al. 2020. Nat Biotechnol. 38:947. PubMed
  81. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  82. Zhang S, et al. 2021. Cell. 184(8):2151-2166.e16. PubMed
  83. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  84. Siew JJ, et al. 2019. Nat Commun. 10:3473. PubMed
  85. Verma M, et al. 2018. Brain Behav Immun. 69:223. PubMed
  86. Duarte N, et al. 2018. Hepatol Commun. 0.833333333. PubMed
  87. Di Gioia M, et al. 2020. Nat Immunol. 21:42. PubMed
  88. Pham THM, et al. 2020. Cell Host & Microbe. 27(1):54-67.e5.. PubMed
  89. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  90. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  91. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  92. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  93. Kasper M, et al. 2021. Elife. 10:. PubMed
  94. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  95. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  96. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  97. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  98. Caiado F, et al. 2013. Cancer Res. 73:4233. PubMed
  99. Lin T, et al. 2015. PLoS One. 10: e0138335. PubMed
  100. Esmaili S, et al. 2021. Cell Systems. 12(5):432-445.e7. PubMed
  101. Jeong D, et al. 2021. eLife. 0.416666666666667. PubMed
  102. Luff DH, et al. 2021. Front Immunol. 631271:12. PubMed
  103. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  104. Privratsky JR, et al. 2018. Am J Physiol Renal Physiol. 315:F682. PubMed
  105. Luo W, et al. 2019. Mol Med Rep. 20:1007. PubMed
  106. Mayers S, et al. 2019. BMC Biotechnol. 19:21. PubMed
  107. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  108. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  109. Kan C, et al. 2022. Bone Res. 10:62. PubMed
  110. Zhang J, et al. 2021. J Leukoc Biol. 110:485. PubMed
  111. Qiu F, et al. 2022. J Cancer. 13:2893. PubMed
  112. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  113. Hou H, et al. 2021. Front Cell Dev Biol. 9:737003. PubMed
  114. Antunes KH, et al. 2022. Front Immunol. 13:867022. PubMed
  115. Liang P, et al. 2022. Mol Biomed. 3:14. PubMed
  116. Wu Q, et al. 2022. Cell Mol Life Sci. 79:137. PubMed
  117. Li Y, et al. 2022. Clin Transl Immunology. 11:e1362. PubMed
  118. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  119. Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed
  120. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  121. Periasamy S, et al. 2011. J Leukoc Biol. 90:493. PubMed
  122. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  123. Zong Z, et al. 2019. Front Immunol. 10:1643. PubMed
  124. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  125. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  126. Marchingo JM, et al. 2020. eLife. 9:e53725.. PubMed
  127. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  128. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  129. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  130. Shen Y, et al. 2022. CNS Neurosci Ther. 28:46. PubMed
  131. Rao X, et al. 2022. Cell Death Dis. 13:891. PubMed
  132. Geng T, et al. 2022. Methods Mol Biol. 2585:71. PubMed
  133. Lee M, et al. 2014. PLoS One. 9:112666. PubMed
  134. Velázquez K, et al. 2016. Am J Physiol Gastrointest Liver Physiol. 311: G699 - G712. PubMed
  135. Chi Z, et al. 2020. Molecular Cell. 80(1):43-58.e7. PubMed
  136. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  137. Perez–Zsolt D, et al. 2019. Front Immunol. 0.989583333. PubMed
  138. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  139. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  140. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  141. Ye Z, et al. 2019. Mediators Inflamm. 2019:8709583. PubMed
  142. Yuan F, et al. 2022. Front Immunol. 13:798583. PubMed
  143. Forbester JL, et al. 2020. J Virol. 94:. PubMed
  144. Wu H, et al. 2022. Biomolecules. 12:. PubMed
  145. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  146. Gao H, et al. 2021. Cells. 10:. PubMed
  147. Saitoh BY, et al. 2021. Brain Behav Immun. 95:362. PubMed
  148. Marks KE, et al. 2021. Cell Reports. 35(13):109303. PubMed
  149. Ohgomori T, et al. 2020. Neuropharmacology. 176:108227. PubMed
  150. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  151. Köchl R, et al. 2020. Elife. 9:00. PubMed
  152. Lin D, et al. 2015. Proc Natl Acad Sci U S A. 112: 11324-11329. PubMed
  153. Madan-Lala R, et al. 2014. J Immunol. 192:4263. PubMed
  154. Ippolito G, et al. 2014. Proc Natl Acad Sci U S A. 111:998. PubMed
  155. Knolle MD et al. 2018. Frontiers in immunology. 1.925 . PubMed
  156. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  157. Wang F, et al. 2018. Carcinogenesis. 39:889. PubMed
  158. Greenwald AC, et al. 2019. J Exp Med. 216:215. PubMed
  159. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  160. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  161. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  162. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  163. Yee PP, et al. 2020. Nat Commun. 4.225. PubMed
  164. Dong S, et al. 2021. Nature. 591:117. PubMed
  165. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  166. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  167. Yadav P, et al. 2021. J Immunol. 206:2888. PubMed
  168. Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
  169. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  170. Bao C, et al. 2021. Infect Immun. 89:. PubMed
  171. Tan A, et al. 2012. Mol Pharmacol. 9:2710. PubMed
  172. Cappello P, et al. 2013. Gastroenterology. 144:1098. PubMed
  173. Meraz I, et al. 2014. PLoS One. 9:94703. PubMed
  174. Aebischer D, et al. 2014. PLoS One. 9:99297. PubMed
  175. Lehmann M, et al. 2016. J Leukoc Biol. 99: 1057 - 1064. PubMed
  176. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  177. Koivisto CS, et al. 2020. Neoplasia. 1.252777778. PubMed
  178. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  179. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  180. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  181. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  182. Dmitrieva‐Posocco O et al. 2019. Immunity. 50(1):166-180 . PubMed
  183. Tavazoie MF, et al. 2018. Cell. 172:825. PubMed
  184. Wang Q, et al. 2018. Nat Commun. 9:559. PubMed
  185. Reismann D, et al. 2017. Nat Commun.. 10.1038/s41467-017-01538-9. PubMed
  186. Zhou H, et al. 2022. Oncoimmunology. 11:2057892. PubMed
  187. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  188. Shiraki N, et al. 2022. Stem Cell Reports. 17:221. PubMed
  189. Zhang Y, et al. 2021. J Immunol Res. 2021:5599439. PubMed
  190. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  191. Wen Y, et al. 2020. Hypertension. 869:75. PubMed
  192. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  193. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  194. Osaka M, et al. 2016. Sci Rep. 6:21391. PubMed
  195. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  196. Cho K, et al. 2021. iScience. 24:103117. PubMed
  197. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  198. Bakker W, et al. 2021. Int J Mol Sci. 22:. PubMed
  199. Li H, et al. 2021. Nat Commun. 12:7149. PubMed
  200. Shan C, et al. 2021. Front Immunol. 12:766401. PubMed
  201. Sobecki M, et al. 2021. Nat Commun. 12:4700. PubMed
  202. Nishida J, et al. 2022. STAR Protoc. 3:101306. PubMed
  203. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  204. Miller S, et al. 2016. Acta Biochim Biophys Sin. 48: 334-341. PubMed
  205. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  206. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  207. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  208. Simões FC, et al. 2020. Nat Commun. 0.875. PubMed
  209. Ku AT et al. 2017. eLife. 6 pii: e23242. PubMed
  210. Dong L, et al. 2022. Cells. 11:. PubMed
  211. Li Y, et al. 2022. Front Cardiovasc Med. 9:830781. PubMed
  212. Tang C, et al. 2021. Theranostics. 11:9791. PubMed
  213. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  214. Gopinath A, et al. 2022. NPJ Parkinsons Dis. 8:72. PubMed
  215. Sun S, et al. 2021. Front Immunol. 12:777665. PubMed
  216. Lei J, et al. 2021. Theranostics. 4251:11. PubMed
  217. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  218. Chen X, et al. 2016. PLoS One. 11:e0168861. PubMed
  219. Uto T, et al. 2016. Nat Commun. 7: 11273. PubMed
  220. Leon-Rico D, et al. 2015. Lab Anim. 49:132. PubMed
  221. Jäger M, et al. 2018. Antioxid Redox Signal. 30. PubMed
  222. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  223. Liu D, et al. 2020. Front Pharmacol. 11:204. PubMed
  224. Merlo LM, et al. 2020. Clin Pathol. 13:2632010X20951812. PubMed
  225. Quenum Zangbede FO, et al. 2018. J Neurosci. 38:6737. PubMed
  226. Taddio MF, et al. 2021. Mol Imaging Biol. 23:196. PubMed
  227. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  228. Liu P, et al. 2022. iScience. 25:103867. PubMed
  229. Vasudevan SO, et al. 2022. Cell Rep. 39:110755. PubMed
  230. Ryan NM, et al. 2022. Front Immunol. 13:932742. PubMed
  231. Niemi JP, et al. 2020. Methods Mol Biol. 2143:207. PubMed
  232. Dionisio-Santos DA, et al. 2021. Front Neurosci. 15:758677. PubMed
  233. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  234. Ding X, et al. 2015. J Immunol. 194:4251. PubMed
  235. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  236. Takesue S, et al. 2020. Int J Oncol. 56:596. PubMed
  237. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  238. Penkert RR, et al. 2020. Obesity (Silver Spring). 1631:28. PubMed
  239. Zhuo Y, et al. 2018. Oncol Rep. 40:2147. PubMed
  240. Ponzetta A, et al. 2020. Cell. 178(2):346-360.e24.. PubMed
  241. Ibrahim ML, et al. 2018. Cell Rep. 25:3036. PubMed
  242. Lima-Junior D, et al. 2017. J Immunol. 10.4049/jimmunol.1700258. PubMed
  243. Stevenson ER, et al. 2022. J Pharmacol Exp Ther. 382:356. PubMed
  244. Chen Y, et al. 2022. Life Sci. 306:120826. PubMed
  245. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  246. Dong R, et al. 2021. Frontiers in Immunology. 12:620238. PubMed
  247. Chen S, et al. 2020. Allergy Asthma Immunol Res. 0.922222222. PubMed
  248. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  249. Chen F, et al. 2016. J Immunol. 196: 4390 - 4399. PubMed
  250. Nechama M, et al. 2018. Nat Commun. 9:1603. PubMed
  251. Wang T et al. 2018. Immunity. 49(3):504-514 . PubMed
  252. Adachi Y, et al. 2019. Nat Commun. 10:3883. PubMed
  253. Ohgomori T et al. 2019. J Comp Neurol. 528(1):14-31 . PubMed
  254. Li S, et al. 2019. Front Neurol. 1.036805556. PubMed
  255. He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
  256. Hua X, et al. 2021. Front Immunol. 12:706027. PubMed
  257. Feng L, et al. 2022. Signal Transduct Target Ther. 7:21. PubMed
  258. Zhang MS, et al. 2022. Nat Commun. 13:954. PubMed
  259. Zhang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  260. Ostapoff K, et al. 2013. Mol Cancer Ther. 12:1190. PubMed
  261. Macagno M, et al. 2014. J Immunol. 192:5434. PubMed
  262. Chou H, et al. 2015. Proc Natl Acad Sci U S A. 112:2175. PubMed
  263. Quan S, et al. 2015. J Immunol. 194:4175. PubMed
  264. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  265. Yamamuro T, et al. 2020. Nat Commun. 3.340277778. PubMed
  266. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  267. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  268. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  269. Kitamura K, et al. 2019. Int J Cardiol Heart Vasc. 23:100344. PubMed
  270. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  271. Grayczyk JP et al. 2017. Cell host & microbe. 22(5):678-687 . PubMed
  272. Alter C et al. 2019. Am J Physiol Heart Circ Physiol. 317(1):H190-H200 . PubMed
  273. Spolski R et al. 2019. Elife. 8 pii: e45501. PubMed
  274. Tian D, et al. 2019. Nat Commun. 10:4246. PubMed
  275. Li Q, et al. 2022. Front Oncol. 12:841977. PubMed
  276. Rao L, et al. 2020. Nat Commun. 11:4909. PubMed
  277. Zhang GL, et al. 2020. Matrix Biol. 93:25. PubMed
  278. Chen Y, et al. 2022. Nat Commun. 13:4468. PubMed
  279. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  280. Mihalik NE, et al. 2021. AAPS PharmSciTech. 22:191. PubMed
  281. Li Y, et al. 2022. STAR Protoc. 3:101364. PubMed
  282. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  283. Zhou H, et al. 2021. Cell Death Discov. 7:332. PubMed
  284. Li K, et al. 2020. J Cell Mol Med. 24:13115. PubMed
  285. Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
  286. Roderick J, et al. 2014. Proc Natl Acad Sci U S A. 111:14436. PubMed
  287. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  288. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  289. Fox D, et al. 2020. Nat Commun. 0.986111111. PubMed
  290. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  291. Chan JY, et al. 2019. Diabetologia. 62:993. PubMed
  292. Adzika GK, et al. 2021. Front Cell Dev Biol. 9:719351. PubMed
  293. Tang S, et al. 2022. Virol J. 19:32. PubMed
  294. Cui Y, et al. 2022. Front Oncol. 12:732860. PubMed
  295. Deliyannis G, et al. 2021. JCI Insight. 6:. PubMed
  296. Tähtinen S, et al. 2022. Nat Immunol. 23:532. PubMed
  297. Patel C, et al. 2022. Curr Protoc. 2:e400. PubMed
  298. Wagner AK, et al. 2022. iScience. 25:105137. PubMed
  299. Erin N, et al. 2015. Brain Behav Immun. 48: 174-185. PubMed
  300. Zhang T, et al. 2020. JCI Insight. 5:00. PubMed
  301. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  302. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  303. Yang X, et al. 2021. Bioact Mater. 3150:6. PubMed
  304. Woods B, et al. 2019. Clin Cancer Res. 25:5901. PubMed
  305. Han P, et al. 2020. Sci Adv. 6:eaaz1580. PubMed
  306. Calvente CJ, et al. 2019. J Clin Invest. 130:4091. PubMed
  307. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  308. Ortiz A, et al. 2019. Cancer Cell. 35:33:00. PubMed
  309. Uehara M, et al. 2019. Sci Rep. 9:6535. PubMed
  310. Wang Y, et al. 2022. Nat Commun. 13:1454. PubMed
  311. Zhang XL, et al. 2022. J Am Heart Assoc. 11:e023800. PubMed
  312. Wang X, et al. 2022. Elife. 11:. PubMed
  313. Adzika GK, et al. 2021. Front Cardiovasc Med. 8:719805. PubMed
  314. Chen X, et al. 2021. Cell Death Dis. 12:1123. PubMed
  315. Chen J, et al. 2021. Oncol Lett. 21:409. PubMed
  316. Liu SS, et al. 2021. Immunity. :. PubMed
  317. Zhou JH, et al. 2020. Onco Targets Ther. 7.278472222. PubMed
  318. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  319. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  320. Zhong B, et al. 2013. Sci Signal. 6:35. PubMed
  321. Bartley A, et al. 2018. Front Physiol. 9:1593. PubMed
  322. Geng S, et al. 2019. Sci Adv. 5:eaav2309. PubMed
  323. Arima Y et al. 2017. eLife. 6 pii: e25517. PubMed
  324. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  325. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  326. Liu Z, et al. 2020. STAR Protoc. 1:100029. PubMed
  327. Luo ZW, et al. 2021. Int J Nanomedicine. 16:2949. PubMed
  328. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  329. Lee A, et al. 2022. Nat Commun. 13:549. PubMed
  330. Shin SH, et al. 2022. Clin Exp Otorhinolaryngol. . PubMed
  331. Palma A, et al. 2022. Front Cell Dev Biol. 10:841548. PubMed
  332. Jia J, et al. 2022. Nat Commun. 13:6804. PubMed
  333. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  334. Chen MB, et al. 2020. Cell Rep. 30:4418. PubMed
  335. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  336. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  337. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  338. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  339. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  340. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  341. Xu Z, et al. 2022. Cell Death Dis. 13:502. PubMed
  342. Wang S, et al. 2022. Blood. 140:171. PubMed
  343. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  344. Davis FM, et al. 2021. J Exp Med. 218:. PubMed
  345. Wu KKL, et al. 2021. Nat Commun. 12:6637. PubMed
  346. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  347. Xue Y, et al. 2020. Sci Rep. 10:22265. PubMed
  348. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  349. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  350. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
  351. Koronyo Y, et al. 2015. Brain. 138: 2399-2422. PubMed
  352. Zhao Y, et al. 2013. J Leukoc Biol. 94:1103. PubMed
RRID
AB_312788 (BioLegend Cat. No. 101205)
AB_312789 (BioLegend Cat. No. 101206)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Spark PLUS UV™ 395 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account