APC anti-human CD50 (ICAM-3) Antibody

Pricing & Availability
CBR-IC3/1 (See other available formats)
Regulatory Status
Other Names
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with CBR-IC3/1 APC
  • CBR-IC3slash1_APC_021009.jpg
    Human peripheral blood lymphocytes stained with CBR-IC3/1 APC
See APC spectral data
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330011 25 tests 100,00€
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CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, αL2) integrin.

Product Details
Technical Data Sheet (pdf)

Product Details

Human, Baboon, Cynomolgus
Antibody Type
Host Species
SKW3 cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications include: immunoprecipitation1 and blocking1-3.

Application References
  1. deFougerolles AR and Springer TA, et al. 1992. J. Exp. Med. 175:185. (IP, Block)
  2. Geijtenbeek T, et al. 2000. Cell 100:575. (Block)
  3. Giannoni E, et al. 2003. J Biol. Chem. 278:36763. (Block)
Product Citations
  1. Sugden SM, et al. 2017. J Virol. 91:e02445. PubMed
  2. Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed
  3. Grandclaudon M, et al. 2019. Cell. 179:432. PubMed
AB_1227570 (BioLegend Cat. No. 330011)

Antigen Details

Ig superfamily, type I membrane protein, 130 kD
Thymocytes, T and B cells, monocytes, granulocytes, endothelial cells
Adhesion, costimulation
CD11a/CD18 (LFA-1), integrin αL2
Cell Type
Thymocytes, T cells, B cells, Monocytes, Granulocytes, Endothelial cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Costimulatory Molecules
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Valent P, et al. 2001. Immunol. Rev. 179:74.

Gene ID
3385 View all products for this Gene ID
View information about CD50 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 06/18/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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