- 2E1B02 (See other available formats)
- Regulatory Status
- Other Names
- GP130, GP-130, IL6ST, IL-6Rβ, Oncostatin M Receptor, Oncostatin-M receptor subunit alpha
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD130, also known as gp130 (glycoprotein 130), IL6ST (IL-6-receptor-associated signal transducer), or common β chain, is a member of the hematopoietic cytokine receptor family. CD130 is a common subunit associated with the receptors for several cytokines, such as IL-6, IL-11, Oncostatin M (OSM), CNTF (ciliary neurotrophic factor), CT-1, Neuropoietin (NP), and IL-27. CD130 participates in the JAK-STAT signaling pathway and is expressed on T cells, activated B cells, monocytes, plasma cells, and endothelial or epithelial cells.Product Details
- Antibody Type
- Host Species
- GP130 (23-619aa) recombinant protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Red Laser (633 nm)
- Product Citations
AB_2563403 (BioLegend Cat. No. 362005)
AB_2563404 (BioLegend Cat. No. 362006)
- 130 kD type I transmembrane glycoprotein.
T cells, activated B cells, monocytes, plasma cells, endothelial cells and epithelial cells.
- Common β subunit of IL-6 receptor family, plays a role in signal transduction.
- IL-6, IL-11, OSM, CNTF, CT-1, NP, IL-27.
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Monocytes, Plasma cells, T cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Arzt E, et al. 2001. J. Clin. Invest. 108:1729.
2. Bravo J, et al. 2000. EMBO J. 19:2399.
3. Wang XJ, et al. 1998. Blood 91:3308.
4. Hibi. M, et al. 1990. Cell. 63:1149.
5. Schlossman S, et al. 1995. ed. Leukocyte Typing V. New York. Oxford University Press.
- Gene ID
- 3572 View all products for this Gene ID
- View information about CD130 on UniProt.org
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