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APC/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, ? APC/Cyanine7 isotype control (open histogram).
  • 30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
    C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, ? APC/Cyanine7 isotype control (open histogram).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
103115 25 µg 98 CHF
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103116 100 µg 196 CHF
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  2. Naito H, et al. 2020. Nature Protocols. 15(3):1066-1081. PubMed
  3. Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed
  4. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  5. Contijoch EJ et al. 2019. eLife. 8 pii: e40553. PubMed
  6. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  7. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  8. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  9. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  10. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  11. Stefkovich M, et al. 2021. Mol Metab. 54:101357. PubMed
  12. Wang Q, et al. 2020. Radiat Environ Biophys. 59:89. PubMed
  13. Kim MY, et al. 2021. JCI Insight. 6:. PubMed
  14. De Vries LCS, et al. 2021. J Crohns Colitis. 15:617. PubMed
  15. Bernasconi R, et al. 2021. EMBO Mol Med. :e14392. PubMed
  16. Miranda K, et al. 2022. iScience. 25:104994. PubMed
  17. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  18. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  19. Ren D, et al. 2022. STAR Protoc. 3:101217. PubMed
  20. Urban SK, et al. 2020. Liver Int. 40:3103. PubMed
  21. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  22. Rosenkranz SC, et al. 2021. eLife. 10:00. PubMed
  23. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  24. Page N, et al. 2018. Immunity. 48:937. PubMed
  25. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  26. Ajina R, et al. 2019. Oncoimmunology. 8:e1577127. PubMed
  27. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  28. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  29. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  30. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  31. Wu SY, et al. 2022. Mol Cancer. 21:84. PubMed
  32. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  33. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  34. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  35. Fan L, et al. 2021. Cancers (Basel). 13:. PubMed
  36. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  37. Evans H, et al. 2015. J Immunol. 195: 2973 - 2984. PubMed
  38. Cardona S, et al. 2015. ASN Neuro. 7: 1759091415608204. PubMed
  39. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  40. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  41. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  42. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  43. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  44. Blecher-Gonen R, et al. 2019. Cell Syst. 8:109. PubMed
  45. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  46. Pluchino N, et al. 2020. J Cell Mol Med. 24:2464. PubMed
  47. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  48. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  49. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  50. Baram T, et al. 2021. Cells. 10:. PubMed
  51. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  52. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  53. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  54. Adrover JM, et al. 2022. JCI Insight. 7:. PubMed
  55. Steubing RD, et al. 2022. Brain Behav Immun Health. 24:100493. PubMed
  56. Lu H, et al. 2021. Autophagy. 17:2511. PubMed
  57. Kawashima N, et al. 2022. Nat Commun. 13:1624. PubMed
  58. Zhu S, et al. 2022. Front Pharmacol. 13:996635. PubMed
  59. Palacios LM, et al. 2022. Biology (Basel). 11:. PubMed
  60. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  61. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  62. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  63. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  64. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  65. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  66. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  67. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  68. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  69. Biswas S, et al. 2021. Nature. 591:464. PubMed
  70. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  71. Shibata K, et al. 2014. J Immunol. 192:2210. PubMed
  72. Mantia-Smaldone G, et al. 2014. Gynecol Oncol. 133:584. PubMed
  73. Rybalko V, et al. 2015. PLoS One. 10: 0145550. PubMed
  74. AR P, et al. 2016. Circ Res. 118: 400-409. PubMed
  75. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  76. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  77. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  78. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  79. Ganeshan K et al. 2019. Cell. 177(2):399-413 . PubMed
  80. Wiley CD, et al. 2019. JCI Insight. 4:e130056. PubMed
  81. Krasteva G, et al. 2011. Proc Natl Acad Sci U S A. 108:9478. PubMed
  82. Yoon Y, et al. 2021. Cancers (Basel). 13: . PubMed
  83. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  84. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  85. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  86. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  87. Jung BG, et al. 2022. PLoS Pathog. 18:e1010454. PubMed
  88. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  89. Marangoni F, et al. 2021. Cell. . PubMed
  90. Wang LT, et al. 2021. STAR Protocols. 2(1):100337. PubMed
  91. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  92. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  93. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
  94. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  95. Huang B, et al. 2020. Cell. 179(5):1160-1176.e24.. PubMed
  96. Ning F, et al. 2019. J Exp Med. 216:1396. PubMed
  97. Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
  98. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  99. Evans R, et al. 2019. Cell Rep. 27:1967. PubMed
  100. Hammond TR, et al. 2019. Immunity. 50:253. PubMed
  101. Schönfeld M, et al. 2021. Alcohol Clin Exp Res. 45:1980. PubMed
  102. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  103. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  104. Liu M, et al. 2020. Cell Rep. 32:107990. PubMed
  105. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  106. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  107. Chi Z, et al. 2020. Molecular Cell. 80(1):43-58.e7. PubMed
  108. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  109. Commerford CD et al. 2018. Cell reports. . PubMed
  110. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  111. Yousef H, et al. 2018. Bio Protoc. 8:22. PubMed
  112. Willingham SB, et al. 2018. Cancer Immunol Res. 6:1136. PubMed
  113. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  114. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  115. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  116. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  117. Hillel–Karniel C, et al. 2020. Cell Reports. 30(3):807-819.e4.. PubMed
  118. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  119. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  120. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  121. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  122. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  123. Zhang X, et al. 2020. Elife. 9:00. PubMed
  124. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  125. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  126. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  127. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  128. Soldevilla MM, et al. 2019. Mol Ther. 27:1878. PubMed
  129. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  130. Li Y, et al. 2019. Sci Rep. 9:6932. PubMed
  131. Mifflin L, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  132. Stewart JM, et al. 2020. ACS Biomater Sci Eng. 6:5941. PubMed
  133. Gao H, et al. 2021. Cells. 10:. PubMed
  134. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  135. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  136. Veremeyko T, et al. 2012. J Vis Exp. 65: 4097. PubMed
  137. Fu H, et al. 2020. Front Immunol. 11:595813. PubMed
  138. Oladiran O, et al. 2021. J Neuroinflammation. 77:18. PubMed
  139. Ayaub E,et al. 2017. Sci Rep.. 10.1038/s41598-017-13511-z. PubMed
  140. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  141. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  142. Alikhanyan K, et al. 2021. Cancers (Basel). 13:. PubMed
  143. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  144. Ali M, et al. 2022. JCI Insight. 7:. PubMed
  145. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  146. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  147. Ghandhi SA, et al. 2022. Sci Rep. 12:14124. PubMed
  148. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  149. Toubal A, et al. 2020. Nat Commun. 3755:11. PubMed
  150. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  151. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  152. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  153. Martina M, et al. 2014. J Vis Exp. 87: 51192. PubMed
  154. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  155. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  156. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  157. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  158. Neuhöfer P, et al. 2021. Nature. 597:715. PubMed
  159. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  160. Hum NR, et al. 2022. Front Oncol. 12:928474. PubMed
  161. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  162. Selvaraj UM, et al. 2021. Brain Behav Immun. 95:502. PubMed
  163. Ying T, et al. 2021. Am J Physiol Endocrinol Metab. 320:E1148. PubMed
  164. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  165. Momin N, et al. 2022. Nat Commun. 13:109. PubMed
  166. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  167. Pilones KA, et al. 2020. Cancer Immunol Res. 8:1054. PubMed
  168. Abramowski P, et al. 2014. J Neuroimmunol. 274:111. PubMed
  169. Hoeksema M, et al. 2015. J Immunol. 194:3909. PubMed
  170. Dhanwani R, et al. 2020. Sci Adv. 6:eaba3688. PubMed
  171. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  172. Cardenas JJ, et al. 2020. Methods Enzymol. 415:631. PubMed
  173. Alikhanyan K, et al. 2020. Immun Inflamm Dis. 8:181. PubMed
  174. Cheng Y, et al. 2019. Clin Cancer Res. 25:2621. PubMed
  175. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  176. Yang Y, et al. 2022. Elife. 11:. PubMed
  177. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  178. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  179. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  180. Gierut J, et al. 2015. Stem Cell Res. 15: 165-171. PubMed
  181. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  182. Haka A, et al. 2012. PLoS One. 7:e44823. PubMed
  183. Kaya B, et al. 2020. Cell Reports. 32(5):107979. PubMed
  184. Sztwiertnia I, et al. 2020. PLoS One. 15:e0233789. PubMed
  185. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  186. Wang R, et al. 2022. Front Immunol. 13:947756. PubMed
  187. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  188. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  189. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  190. Clement CC, et al. 2021. Nat Commun. 12:4447. PubMed
  191. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  192. Huetter J, et al. 2020. Cancer Immunol Res. 0.954861111. PubMed
  193. Favuzzi E, et al. 2021. Cell. 184(15):4048-4063.e32. PubMed
  194. DiToro D, et al. 2020. Immunity. 650:52. PubMed
  195. Veremeyko T, et al. 2019. J Neurosci Res. 97:162. PubMed
  196. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  197. Kim MY, et al. 2018. Cell. 173:1439. PubMed
  198. Camara A, et al. 2019. Immunity. 50:1467. PubMed
  199. Michaelis KA, et al. 2019. Brain Behav Immun. 82:338. PubMed
  200. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  201. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  202. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  203. Zhang R, et al. 2022. Front Pharmacol. 13:870848. PubMed
  204. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  205. Li D, et al. 2022. Emerg Microbes Infect. 11:2248. PubMed
  206. Ou YC, et al. 2020. ACS Nano. 1.035416667. PubMed
  207. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  208. Zelco A, et al. 2020. Front Cell Neurosci. 0.75625. PubMed
  209. Wang LT, et al. 2020. Cell Rep. 32:108188. PubMed
  210. Hadas R, et al. 2020. JCI Insight. 5:00. PubMed
  211. Stock M, et al. 2015. Osteoarthritis Cartilage. 23: 1221-1225. PubMed
  212. Draper D, et al. 2012. J Immunol. 188:5327. PubMed
  213. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  214. Godwin MS, et al. 2019. JCI Insight. 4:e126070. PubMed
  215. Yuan X, et al. 2017. Elife. 6:e29540. PubMed
  216. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  217. Selvaraj UM et al. 2018. Endocrinology. 159(11):3848-3859 . PubMed
  218. Pinho–Ribeiro FA, et al. 2018. Cell. 173:1083. PubMed
  219. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  220. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  221. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  222. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  223. Wang X, et al. 2022. Front Immunol. 13:864984. PubMed
  224. Galani IE, et al. 2022. STAR Protoc. 3:101151. PubMed
  225. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  226. Martina M, et al. 2016. J Am Soc Nephrol. 27: 1113-1123. PubMed
  227. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  228. Wakabayashi T et al. 2018. Cell stem cell. 22(3):384-397 . PubMed
  229. Kaiser T, et al. 2019. Eneuro. 6. PubMed
  230. El Agha E, et al. 2017. Cell Stem Cell. 1.014583333. PubMed
  231. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  232. Ben-Moshe S, et al. 2019. Nat Metab. 1:899. PubMed
  233. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  234. Lu Z, et al. 2021. J Clin Invest. 131:. PubMed
  235. Luo M, et al. 2021. J Immunol. 207:1683. PubMed
  236. Klein S, et al. 2016. J Cell Sci. 129: 2573 - 2585. PubMed
  237. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  238. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  239. Ji L et al. 2019. Immunity. 51(2):272-284 . PubMed
  240. Jiang P, et al. 2018. Nat Med. 24:1550. PubMed
  241. Wang X, et al. 2018. Nat Commun. 9:551. PubMed
  242. Li N, et al. 2022. Nat Commun. 13:7281. PubMed
  243. Pedicone C, et al. 2022. iScience. 25:104170. PubMed
  244. Godwin MS, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 320:L393. PubMed
  245. Reda M, et al. 2022. Nat Commun. 13:4261. PubMed
  246. Li Y, et al. 2022. STAR Protoc. 3:101364. PubMed
  247. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  248. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  249. Kline JM, et al. 2021. J Biol Chem. :100373. PubMed
  250. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  251. Starikova E, et al. 2021. Front Pharmacol. 12:667572. PubMed
  252. Yoldi G, et al. 2016. Cancer Res . 76: 5857 - 5869. PubMed
  253. Ling Y, et al. 2016. Pharmacol Res. S1043-6618(16)31329-9. PubMed
  254. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  255. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  256. Yang C, et al. 2020. Cell Host Microbe. 467:27. PubMed
  257. Armaka M, et al. 2018. Nat Commun. 9:618. PubMed
  258. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  259. Theurich S et al. 2017. Cell metabolism. 26(1):171-184 . PubMed
  260. Martin A, et al. 2018. Oncotarget. 9:28364. PubMed
  261. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  262. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  263. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  264. Gago-Lopez N, et al. 2019. EMBO Mol Med. 11:e10697. PubMed
  265. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  266. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  267. Morein D, et al. 2021. Cells. 10: . PubMed
  268. Yan C, et al. 2022. NPJ Precis Oncol. 6:6. PubMed
  269. Phansalkar R, et al. 2021. Elife. 10:. PubMed
  270. Kim S, et al. 2022. Cancers (Basel). 14:. PubMed
  271. Liu SS, et al. 2021. Immunity. :. PubMed
  272. Ukidve A, et al. 2020. Proc Natl Acad Sci U S A. 117:17727. PubMed
  273. E O’Koren, R Mathew, D Saban 2016. Sci Rep. 6:20636. PubMed
  274. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  275. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  276. Seeling M, et al. 2013. Proc Natl Acad Sci U S A. 110:10729. PubMed
  277. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  278. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  279. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  280. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  281. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  282. Wang Y, et al. 2022. Nat Commun. 13:1454. PubMed
  283. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  284. Zhang X, et al. 2022. J Exp Clin Cancer Res. 41:246. PubMed
  285. Guan D, et al. 2021. Cell Death Dis. 12:431. PubMed
  286. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  287. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  288. Wang J, et al. 2021. Am J Cancer Res. 11:2005. PubMed
  289. Wang X, et al. 2021. Theranostics. 11:209. PubMed
  290. Lux A, et al. 2014. Cell Rep. 10:236. PubMed
  291. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  292. Fox B, et al. 2016. PLoS One. 12: 1006189. PubMed
  293. Parker K, Horn L, Ostrand-Rosenberg S 2016. J Leukoc Biol. 100: 463 - 470.. PubMed
  294. Chen MB, et al. 2020. Cell Rep. 30:4418. PubMed
  295. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
  296. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
  297. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  298. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  299. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  300. Forte E, et al. 2020. Cell Rep. 30:3149. PubMed
  301. Wang J, et al. 2020. J Hematol Oncol. 0.610416667. PubMed
  302. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  303. Cong L, et al. 2021. Breast Cancer Res. 23:51. PubMed
  304. De Micheli AJ, et al. 2020. Am J Physiol Cell Physiol. 319:C885. PubMed
  305. Sibler E, et al. 2021. Cells. 10:. PubMed
  306. Oladiran O, et al. 2021. Front Immunol. 12:720733. PubMed
  307. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  308. Sebastian A, et al. 2021. Cells. 10:. PubMed
  309. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  310. Parent AV, et al. 2021. Cell Reports. 36(7):109538. PubMed
  311. Ito Y, et al. 2021. Cell Reports. 35(4):109052. PubMed
  312. Ma Y, et al. 2021. Developmental Cell. 56(4):478-493.e11. PubMed
  313. Ye Y, et al. 2020. Genome Med. 0.557638889. PubMed
  314. Campisi L, et al. 2016. Nat Immunol. 10.1038/ni.3512. PubMed
  315. Holzapfel B, et al. 2015. Biomaterials. 61: 103-114. PubMed
  316. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  317. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  318. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  319. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  320. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  321. Sun D, et al. 2020. PLoS Pathog. 16:e1008361. PubMed
  322. Zhu Q, et al. 2021. J Am Heart Assoc. 10:e023491. PubMed
  323. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
RRID
AB_312980 (BioLegend Cat. No. 103115)
AB_312981 (BioLegend Cat. No. 103116)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV™ 395 anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 01.30.2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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