PE anti-human RANTES (CCL5) Antibody

Pricing & Availability
Clone
VL1 (See other available formats)
Other Names
CCL5, C-C motif chemokine 5, Small-inducible cytokine A5, T-cell-specific protein RANTES, SIS-delta, T cell-specific protein P228, TCP228, Eosinophil-chemotactic cytokine, EoCP
Isotype
Mouse IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
VL1_PE_CCL5_Antibody_FC_1_010814
Overnight-cultured human peripheral blood lymphocytes (in the presence of monensin) were surface stained with CD3 APC and then intracellularly stained with CCL5 (clone VL1) PE (top) or mouse IgG2b, κ PE isotype control (bottom).
  • VL1_PE_CCL5_Antibody_FC_1_010814
    Overnight-cultured human peripheral blood lymphocytes (in the presence of monensin) were surface stained with CD3 APC and then intracellularly stained with CCL5 (clone VL1) PE (top) or mouse IgG2b, κ PE isotype control (bottom).
  • VL1_PE_CCL5_Antibody_FC_2_010814
See PE spectral data
Cat # Size Price Quantity Avail. Save
515503 25 tests $105
Check Availability


Need larger quantities of this item?
Request Bulk Quote
515504 100 tests $225
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

RANTES (CCL5) is a member of the CC chemokine family. Its mature form consists of 68 amino acid residues. RANTES is a strong chemotractant for monocytes, NK cells, T cells, and eosinphils. RANTES may have important role in mediating immune and inflammatory responses.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Cross-Reactivity: Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Krensky AM, et al. 1997. Methods Enzymol. 287:162.
RRID
AB_2561327 (BioLegend Cat. No. 515503)
AB_2561328 (BioLegend Cat. No. 515504)

Antigen Details

Structure
Human RANTES cDNA is a member of the C-C chemokine family with a MW of around 8 kD. Human and mouse RANTES have 85% homology.
Distribution

Reported to be produced by T cells, platelets, synovial fibroblasts, and some tumor cells.

Function
Able to chemoattract monocytes, NK cells, eosinophils, and T cells.
Interaction
Monocytes, NK cells, T cells, and eosinophils.
Cell Type
Fibroblasts, Platelets, T cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
Cytokines/Chemokines
Antigen References

1. Von Luettichau. et al. 1996. Cytokine 8:89.
2. Schall TJ. 1991. Cytokine 3:165.

Gene ID
6352 View all products for this Gene ID
UniProt
View information about CCL5 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 01/13/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Insert Note Here
Save Close Clear
Lab Timer
Tools
Login/Register
Forgot your password? Reset Password
Request an Account