- S18017D (See other available formats)
- Regulatory Status
- Other Names
- Rat IgG2a, κ
- Ave. Rating
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- Product Citations
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CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).Product Details
- Antibody Type
- Host Species
- Recombinant mouse FcγRI/CD64 (Cat. No. 773806)
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
IHC-F - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. For immunohistochemistry on frozen tissue sections, a concentration range of 5 - 10 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2890725 (BioLegend Cat. No. 161002)
- Ig superfamily, type I glycoprotein, 72 kD
Monocytes, macrophages, mast cells, dendritic cells
- Phagocytosis, ADCC
- Antigen References
1. Schyns J, et al. 2019. Nat. Commun. 3;10(1):3964
2. Langlet C, et al. 2012. J. Immunol. 188 (4) 1751-1760.
- Gene ID
- 14129 View all products for this Gene ID
- View information about CD64 on UniProt.org
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