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PE anti-pig CD8 Antibody

Pricing & Availability
Clone
76-2-11 (See other available formats)
Regulatory Status
RUO
Other Names
CD8a, Leu2 T-lymphocyte antigen, LEU2, MAL, T8, CD8α
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
76-2-11_PE_CD8alpha_Antibody_072622
Porcine peripheral blood lymphocytes were stained with anti-pig CD4a FITC and anti-pig CD8 (clone 76-2-11) PE (left), or mouse IgG1, κ PE isotype control (right).
  • 76-2-11_PE_CD8alpha_Antibody_072622
    Porcine peripheral blood lymphocytes were stained with anti-pig CD4a FITC and anti-pig CD8 (clone 76-2-11) PE (left), or mouse IgG1, κ PE isotype control (right).
See PE spectral data
Cat # Size Price Quantity Check Availability Save
251203 25 µg £95
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251204 100 µg £166
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Description

CD8 is a 35 kD type I transmembrane glycoprotein and is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It functions as a MHC Class I co-receptor for antigen recognition. It is highly expressed in thymocytes, cytotoxic T-cells, and NK cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Pig
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2924500 (BioLegend Cat. No. 251203)
AB_2924500 (BioLegend Cat. No. 251204)

Antigen Details

Structure
Type I transmembrane glycoprotein, expressed as CD8αα homodimer or a CD8αβ heterodimer
Distribution

Thymocytes, suppressor/cytotoxic subpopulation of peripheral T cells

Function
Co-receptor, stabilizes MHC Class I-TCR interaction
Ligand/Receptor
T-cell receptors, MHC-I
Cell Type
NK cells, T cells, Thymocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
  1. Wang W, et al. 2015. Mol Genet Genomics. 290:1447-56.
Gene ID
396627 View all products for this Gene ID
UniProt
View information about CD8 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 07/25/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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