- 3A2A20 (See other available formats)
- Regulatory Status
- Other Names
- POU domain class 5, transcription factor 1 (POU5F1), OCT4, OCT3
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
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Oct4 (Octamer binding transcription factor 4) is an important marker of the undifferentiated state and central regulator of pluripotency in ES cells. When embryonic stem cells are triggered to differentiate, Oct4 is downregulated, thus providing a model for the early events linked to somatic differentiation in the developing embryo. Oct4 is a nuclear protein, with a predicted molecular weight of 39 kD.Product Details
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Host Species
- Partial human Oct4 recombinant protein (1-141aa).
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
AB_2562017 (BioLegend Cat. No. 653703)
AB_2562018 (BioLegend Cat. No. 653704)
- Belongs to the POU transcription factor family, predicted molecular weight of 39 kD
Nuclear protein, expressed in undifferentiated embryonal carcinoma (EC) cells, embryonic stem (ES) cells and embryonic germ (EG) cells
- Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Oct4 is a prime candidate for an early developmental control gene. It also is an important marker of the undifferentiated state and central regulator of pluripotency in ES cells.
- SOX2, SOX8, SOX10, androgen receptor, and ETS2
- Biology Area
- Cell Biology, Immunology, Stem Cells, Transcription Factors
- Antigen References
1. Niwa H, et al. 2000. Nature Genet. 24:372.
2. Wernig M, et al. 2007. Nature 448:318.
3. Pesce M, et al. 2001. Stem Cells 19:271.
- Gene ID
- 5460 View all products for this Gene ID
- View information about Oct4 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
|Purified anti-Oct4 (Oct3)||3A2A20||WB, ICC, ChIP|
|PE anti-Oct4 (Oct3)||3A2A20||ICFC|
|Alexa Fluor® 488 anti-Oct4 (Oct3)||3A2A20||ICFC|
|Brilliant Violet 421™ anti-Oct4 (Oct3)||3A2A20||ICC, ICFC|
|Alexa Fluor® 647 anti-Oct4 (Oct3)||3A2A20||ICC, ICFC|
|Go-ChIP-Grade™ Purified anti-Oct4 (Oct3)||3A2A20||ChIP, WB, ICC|
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