- QA18A21 (See other available formats)
- Regulatory Status
- Other Names
- Leu-19, NKH1
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
AB_2820070 (BioLegend Cat. No. 398803)
AB_2820071 (BioLegend Cat. No. 398804)
- Ig superfamily, single transmembrane or GPI-anchored glycoprotein
NK cells, T subset, neural tissue, some LGL and myeloid leukemias
- Heparin sulfate
- Cell Type
- B cells, Leukemia, Mesenchymal Stem Cells, Neurons, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
- Rosental B, et al. 2011. J Immunol. 187:5693. PubMed
- Correia DV, et al. 2011. Blood. 118:992. PubMed
- Schlecker E, et al. 2014. Cancer Res. 74:3429. PubMed
- Snyder JM, et al. 2014. PLoS One. 9:e107257. PubMed
- Siebert N, et al. 2014. PLoS One. 9:e107692. PubMed
- Rider P, et al. 2015. J Immunol. 195:1705-12. PubMed
- Davis ZB, et al. 2011. J Vis Exp. 49: 2668. PubMed
- Robin JD, et al. 2015. J Vis Exp. 95: 52307. PubMed
- Ames E, et al. 2015. J Immunol. 195: 4010-9. PubMed
- Laroni A, et al. 2016. J Autoimmun. 72:8-18. PubMed
- Pachnio A, et al. 2016. PLoS Pathog. 12:e1005832. PubMed
- Wouters K, et al. 2017. Sci Rep. 7:42665. PubMed
- Gene ID
- 4684 View all products for this Gene ID
- View information about CD56 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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