PE anti-human CD124 (IL-4Rα) Antibody

Pricing & Availability
G077F6 (See other available formats)
Regulatory Status
Other Names
IL-4 receptor α subunit
Mouse IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD19 APC and CD124 (clone G077F6) PE (filled histogram) or mouse IgG2a, κ isotype control PE (open histogram). The data was analyzed by gating on CD19-positive cells.
  • G077F6_PE_070212
    Human peripheral blood lymphocytes were stained with CD19 APC and CD124 (clone G077F6) PE (filled histogram) or mouse IgG2a, κ isotype control PE (open histogram). The data was analyzed by gating on CD19-positive cells.
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355003 25 tests 93€
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355004 100 tests 234€
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CD124, also known as the alpha subunit of IL-4R, is a 140 kD transmembrane glycoprotein. It associates with either the common γ-chain (CD132) to form the type I IL-4R complex, which specifically binds IL-4, or with IL-13Ra1 to form the type II IL-4R heterodimeric complex, which binds and transduces signals from either IL-4 or IL-13.  A truncated form of IL-4Rα exists in the soluble form in biological fluids. CD124 is expressed on human B and T cells as well as a variety of other hematopoietic and non-hematopoietic cells and cell lines.  In B cells, CD124 can bind with IL-4 and IL-13 to regulate IgE antibody production. In T cells, the type I IL-4R (IL-4R/gC) is mostly responsible for Th2 cell expansion by mediating IL-4-dependent activation of the transcription factors in hematopoietic cells. The type II IL-4R (IL-4R/IL-13Ra1) is the main route for non-hematopoietic cell responses to IL-4 or IL-13.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Recombinant human IL-4Rα Fc chimera
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Bal S, et al. 2016. Nat Immunol. 10.1038/ni.3444. PubMed
  2. Li H, et al. 2016. J Immunol. 196: 4064 - 4074. PubMed
  3. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  4. Wu L, et al. 2018. Oncol Lett. 15:9507. PubMed
AB_11218807 (BioLegend Cat. No. 355003)
AB_11219385 (BioLegend Cat. No. 355004)

Antigen Details

140 kD type I transmembrane glycoprotein, associates with common γ chain or IL-13 receptor alpha-1 subunit

B cells, T cells, endothelial cells, cancer cells

Regulates IgE antibody production in B cells, Th2 cell expansion, and IL-4 or IL-13 induced response in non-hematopoietic cells
IL-4, IL-13
Cell Type
B cells, Endothelial cells, T cells
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Signal Transduction, Transcription Factors
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References
  1. Kashiwada M, et al. 2001. J. Immunol. 167:6382.
  2. Gilmour J, et al. 2008. Immunology 124:437.
  3. Hage T, et al. 1999. Cell 97:271.
Gene ID
3566 View all products for this Gene ID
View information about CD124 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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