Purified anti-Pax-6 Antibody (Previously Covance catalog# PRB-278P)

Pricing & Availability
Clone
Poly19013 (See other available formats)
Regulatory Status
RUO
Other Names
Paired box protein Pax-6, oculorhombin, aniridia type II protein, Sey, Protein eyeless, PRB-278P-100
Previously
Covance Catalog# PRB-278P
Isotype
Rabbit Polyclonal IgG
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Product Citations
publications
1-Poly19013_PURE_Pax-6_Antibody_1_091420
Whole cell extracts (15µg total protein) from 293T (human), (left panel) or E17 Ms. brain (mouse brain at day 17 of development), (right panel) were resolved by 4-12% Bis-Tris gel electrophoresis, transferred to PVDF membrane and probed with 1.0 µg/mL (1:2000 dilution) of purified Pax-6 rabbit antibody (clone Poly19013) for 2 hr at RT. Proteins were visualized by chemiluminescence detection using HRP Donkey anti-rabbit IgG Antibody (Cat. No. 406401, 1:3000 dilution). Direct-Blot™ HRP anti-GAPDH antibody (Cat. No. 607904) was used as a loading control at 1:25000 dilution (lower). Lane M:Molecular weight marker.
  • 1-Poly19013_PURE_Pax-6_Antibody_1_091420
    Whole cell extracts (15µg total protein) from 293T (human), (left panel) or E17 Ms. brain (mouse brain at day 17 of development), (right panel) were resolved by 4-12% Bis-Tris gel electrophoresis, transferred to PVDF membrane and probed with 1.0 µg/mL (1:2000 dilution) of purified Pax-6 rabbit antibody (clone Poly19013) for 2 hr at RT. Proteins were visualized by chemiluminescence detection using HRP Donkey anti-rabbit IgG Antibody (Cat. No. 406401, 1:3000 dilution). Direct-Blot™ HRP anti-GAPDH antibody (Cat. No. 607904) was used as a loading control at 1:25000 dilution (lower). Lane M:Molecular weight marker.
  • 2-Poly19013_PURE_Pax-6_Antibody_2_091420
    Whole cell extracts (15 µg total protein) from either untransfected 293E cells or transfected with GFP were resolved by 4-12% Bis-Tris gel electrophoresis, transferred to PVDF membrane and probed with 1.0 µg/mL (1:2000 dilution) of purified Pax-6 rabbit antibody (clone Poly19013) (panel A) or purified anti-GFP antibody (clone 1GFP63, Cat. No. 668206) for 2 hr at RT. Proteins were visualized by chemiluminescence detection using HRP Donkey anti-rabbit IgG Antibody (Cat. No. 406401, 1:3000 dilution) or HRP Goat anti-mouse IgG Antibody (Cat. No. 405306, 1:3000 dilution). Direct-Blot™ HRP anti-GAPDH antibody (Cat. No. 607904) was used as a loading control at 1:25000 dilution (lower).Lane M:Molecular weight marker.
  • 3_Purified_Pax-6_Antibody_IHC_2_021315
    IHC staining of purified anti-Pax-6 antibody (clone Poly19013) on formalin-fixed paraffin-embedded mouse brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 20 µg/ml of the primary antibody for 60 minutes at room temperature. BioLegend's Ultra-Streptavidin (USA) HRP kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
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901302 25 µL 92,00€
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901301 100 µL 281,00€
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Description

Pax6 is a transcription factor present during embryonic development. The encoded protein contains two different binding sites that are known to bind DNA and function as a regulator of gene transcription. It is a key regulatory gene of eye and brain development. Within the brain, the protein is involved in development of specialized cells that process smell. Pax-6 acts as a critical gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. Pax6 serves as a regulator in the coordination and pattern formation required for differentiation and proliferation to successfully take place, ensuring that the processes of neurogenesis and oculogenesis are carried out successfully. As a transcription factor, Pax6 acts at the molecular level in the signaling and formation of the central nervous system. The characteristic paired DNA binding domain of Pax6 utilizes two DNA-binding domains, the paired domain (PD), and the paired-type homeodomain (HD). These domains function separately. An example of this lies in HD’s regulatory involvement in the formation of the lens and retina throughout oculogenesis contrasted by the molecular mechanisms of control exhibited on the patterns of neurogenesis in brain development by PD. The HD and PD domains act in close coordination, giving Pax6 its multifunctional nature in directing molecular signaling in formation of the CNS.

The vertebrate PAX6 locus encodes at least three different protein isoforms, these being the canonical PAX6, PAX6(5a), and PAX6(ΔPD). The canonical PAX6 protein contains an N-terminal paired domain, connected by a linker region to a paired-type homeodomain, and a proline/serine/threonine (P/S/T)-rich C-terminal domain. The paired domain and paired-type homeodomain each have DNA binding activities, while the P/S/T-rich domain possesses a transactivation function. PAX6(5a) is a product of the alternatively spliced exon 5a resulting in a 14 residue insertion in the paired domain which alters the specificity of this DNA binding activity. The nucleotide sequence corresponding to the linker region encodes a set of three alternative translation start codons from which the third PAX6 isoform originates. Collectively known as the PAX6(ΔPD) or pairedless isoforms, these three gene products all lack a paired domain. The pairedless proteins possess molecular weights of 43, 33, or 32kDa, depending on the particular start codon used. PAX6 transactivation function is attributed to the variable length C-terminal P/S/T-rich domain which stretches to 153 residues in human and mouse proteins.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human, Mouse, Rat
Antibody Type
Polyclonal
Host Species
Rabbit
Immunogen
This antibody was generated against the peptide (QVPGSEPDMSQYWPRLQ) derived from the C-terminus of the mouse Pax-6 protein.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB, IHC-P - Quality tested
IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting and formalin-fixed paraffin-embedded immunohistochemical staining of brain tissue. For Western blotting, the suggested use of this reagent is 1.0 µg/mL (1:2000). For immunohistochemistry, a dilution of 1:50 - 1:100 is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody weakly reacts with rat. It has also shown reactivity with GFP and is therefore not recommended for use in GFP-expressing systems (as determined by in-house testing).

Pax-6 has two isoforms in human and mice at 46.6 and 48.2 Kd. This antibody recognizes both. The sequence is highly conserved among Pax-6 of various species. The antibody was subsequently purified on a Protein A column and is useful in studying brain, neuronal and olfactory development in higher eukaryotes.

This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).

Application References

(PubMed link indicates BioLegend citation)
  1. Tang K, et al. 2012. Development. 139:1630. (IF) PubMed
  2. Bandah D, et al. 2007. Invest. Ophthalmol. Vis. Sci. 48:2503. (WB) PubMed
  3. Marquardt T, et al. 2001. Cell. 105:43.
  4. Yamamoto Y, Jeffery WR. 2000. Science. 289:631
  5. Ashery-Padan R, et al. 2000. Genes Dev. 14:2701.
  6. Osumi N, et al. 1997. Development. 124:2961.
  7. Koroma BM, et al. 1997. Invest. Ophthalmol Vis Sci. 38:108.
  8. Davis JA, Reed RR. 1996. J Neurosci. 16:5082. (IHC)
  9. Quadrato G, et al. Nature. 545:48. (IF) PubMed
Product Citations
  1. Sun D, et al. 2017. PLoS One. 12(6):e0179047. PubMed
  2. Zhu Y, et al. 2017. Lab Chip. 10.1039/c7lc00682a. PubMed
  3. Mills T, et al. 2017. PLoS One.. 10.1371/journal.pone.0176905. PubMed
  4. Janssens S, et al. 2018. mSystems. 3. PubMed
  5. Tu J et al. 2018. Stem cell research. 28:29-32 . PubMed
  6. Shafa M, et al. 2018. Front Med (Lausanne). 9:1816. PubMed
  7. Dhumale P, et al. 2018. PLoS One. 9:1544. PubMed
  8. Chau KF, et al. 2018. Elife. 19:E663. PubMed
  9. Luisier R, et al. 2018. Nat Commun. 8:6458. PubMed
  10. Wu X, et al. 2018. Cell. 172:423. PubMed
  11. Shibata S et al. 2018. Cell reports. 25(6):1668-1679 . PubMed
  12. Zhang Y et al. 2018. Cell stem cell. 23(4):516-529 . PubMed
  13. Kim YJ, et al. 2018. Neuron. 100:1180. PubMed
  14. Tripathy R, et al. 2018. Neuron. 100:1354. PubMed
  15. Zahr SK et al. 2018. Neuron. 97(3):520-537 . PubMed
  16. Nakano Y et al. 2018. Cell. 174(3):536-548 . PubMed
  17. Thomas Klein et al. 2018. Stem cell research. 33:171-174 . PubMed
  18. Baizabal JM et al. 2018. Neuron. 98(5):945-962 . PubMed
  19. Thomas Klein et al. 2018. Stem cell research. 31:222-226 . PubMed
  20. Tang Y et al. 2018. Cell reports. 24(5):1355-1362 . PubMed
  21. Le Dréau G, et al. 2018. Elife. 7:e7267. PubMed
  22. Cargnin F, et al. 2018. Neuron. 100:1083. PubMed
  23. Scior A, et al. 2018. EMBO J. 37:282. PubMed
  24. Ing-Esteves S, et al. 2018. J Neurosci. 38:2713. PubMed
  25. Hickmott JW, et al. 2018. Gene Ther. 25:524. PubMed
  26. Han S, et al. 2018. Development. 145:. PubMed
  27. Diacou R et al. 2018. Cell reports. 25(9):2510-2523 . PubMed
  28. Lu HC, et al. 2017. Nat Genet. 49:527. PubMed
  29. Andres LM, et al. 2017. ACS Chem Biol. 12:2030. PubMed
  30. Hoshino A, et al. 2017. Dev Cell. 43:763. PubMed
  31. Goodson NB, et al. 2018. Dev Biol. 434:149. PubMed
  32. Xu D, et al. 2018. PLoS Biol. 16:e2006613. PubMed
  33. Robson JP, et al. 2019. PLoS One. 14:e0210665. PubMed
  34. Lim Y, et al. 2019. Sci Rep. 9:226. PubMed
  35. Ward JM, et al. 2019. Cell Rep. 26:1189. PubMed
  36. Todd L, et al. 2017. Glia. 65:1640. PubMed
  37. Remez LA, et al. 2017. Dev Biol. 432:140. PubMed
  38. Broix L, et al. 2018. Hum Mol Genet. 27:224. PubMed
  39. Bovio PP, et al. 2019. Mol Neurobiol. 56:4273. PubMed
  40. Nowakowski TJ, et al. 2018. Nat Neurosci. 21:1784. PubMed
  41. Ren X, et al. 2019. Cell Rep. 26:3643. PubMed
  42. Wilson CS, et al. 2019. JCI Insight. 5. PubMed
  43. Langer LF, et al. 2019. Elife. 8. PubMed
  44. Zurkirchen L, et al. 2019. Nat Commun. 10:2192. PubMed
  45. Wang H, et al. 2019. Cell Rep. 27:2335. PubMed
  46. Alexander JM et al. 2019. Elife. 8 pii: e41769. PubMed
  47. Palencia–Campos A, et al. 2017. Hum Mol Genet. 26:4556. PubMed
  48. Jin J, et al. 2019. PLoS One. 14:e0219362. PubMed
  49. Dominguez Gonzalez B, et al. 2018. Hum Mol Genet. 27:2154. PubMed
  50. Roy A et al. 2019. Elife. 8 pii: e45961. PubMed
  51. Nazir FH, et al. 2018. Neurochem Int. 121:38. PubMed
  52. Docampo–Seara A, et al. 2019. Brain Struct Funct. 224:2325. PubMed
  53. Wang S, et al. 2019. Protein Cell. 10:1. PubMed
  54. Kawaue T, et al. 2019. Nat Commun. 10:2780. PubMed
  55. Karzbrun E, et al. 2018. Nat Phys. 14:515. PubMed
  56. Segarra M, et al. 2018. Science. 361:eaao2861. PubMed
  57. Ooi J, et al. 2019. Cell Rep. 26:2494. PubMed
  58. Liu Z, et al. 2019. Cell Rep. 27:3832. PubMed
  59. Bashford AL, et al. 2019. J Pathol. 248:396. PubMed
  60. Hu XL, et al. 2017. Neuron. 95:309. PubMed
  61. Ibañez Rodriguez MP et al. 2018. The Journal of comparative neurology. 526(15):2462-2481 . PubMed
  62. Todd L, et al. 2018. Stem Cells. 36:392. PubMed
  63. Wang Q, et al. 2017. Curr Biol. 27:1791. PubMed
  64. Docampo–Seara A, et al. 2018. Brain Struct Funct. 223:3593. PubMed
  65. Mochizuki T, et al. 2017. Development. 144:708. PubMed
  66. Zhang X, et al. 2019. Protein Cell. 10:649. PubMed
  67. Watanabe Y, et al. 2018. Development. 145. PubMed
  68. Kurabayashi N, et al. 2018. Development. 145. PubMed
  69. Postel M, et al. 2019. BMC Bioinformatics. 20:470. PubMed
  70. Sanchez–Guardado L, et al. 2019. Elife. 8:e46675. PubMed
  71. Del Toro D et al. 2017. Cell. 169(4):621-635 . PubMed
  72. Peter CJ, et al. 2019. Nat Commun. 10:4112. PubMed
  73. Liu J et al. 2017. Cell stem cell. 21(5):635-649 . PubMed
  74. Chang CH, et al. 2019. Dev Cell. 48:184. PubMed
  75. Klein T et al. 2019. Stem cell research. 1724:56:00 . PubMed
  76. Uzquiano A, et al. 2019. Cell Rep. 28:1596. PubMed
  77. Wu Z, et al. 2019. Neuron. 101:635. PubMed
  78. Gao F et al. 2019. Mol Cell. 75(5):891-904 . PubMed
  79. Alzu'bi A et al. 2019. Journal of anatomy. 235(3):555-568 . PubMed
  80. Pollen AA, et al. 2019. Cell. 176:743. PubMed
  81. Lavado A et al. 2018. Dev Cell. 47(5):576-591 . PubMed
  82. Homman‐Ludiye J et al. 2018. The Journal of comparative neurology. 526(17):2870-2883 . PubMed
  83. Cliff TS et al. 2017. Cell stem cell. 21(4):502-516 . PubMed
  84. Forrest MP, et al. 2017. Cell Stem Cell. 1.086805556. PubMed
  85. Beattie R et al. 2017. Neuron. 94(3):517-533 . PubMed
  86. Gabriel E et al. 2017. Cell stem cell. 20(3):397-406 . PubMed
  87. Sano N et al. 2017. Frontiers in cellular neuroscience. 0.54375 . PubMed
  88. Parween S, et al. 2018. Front Cell Neurosci. 0.746527778. PubMed
  89. Miesfeld JB, et al. 2018. Sci Rep. 8:10195. PubMed
  90. Chen Y, et al. 2019. Methods Mol Biol. 1919:59:00. PubMed
  91. Velasco S, et al. 2019. Nature. 570:523. PubMed
  92. Moore D, et al. 2019. Stem Cells Int. 2019:8710180. PubMed
  93. Bonnefont J, et al. 2019. Neuron. 103:1096. PubMed
  94. Wörsdörfer P, et al. 2019. Sci Rep. 9:15663. PubMed
  95. Panagiotakos G, et al. 2019. Elife. 8:e51037. PubMed
  96. Pandey PR, et al. 2019. Int J Mol Sci. 0.936805556. PubMed
  97. Shafa M, et al. 2019. Int J Mol Sci. 0.95. PubMed
  98. Laan L, et al. 2020. Clin Epigenetics. 12:09. PubMed
  99. Matsumura K, et al. 2020. Nat Commun. 11:859. PubMed
  100. Plaza Reyes A, et al. 2020. Nat Commun. 11:1609. PubMed
  101. Fregeac J, et al. 2020. Mol Autism. 11:22. PubMed
  102. Popovitchenko T, et al. 2020. Nat Commun. 11:1674. PubMed
  103. Mirjalili Mohanna SZ, et al. 2020. Mol Ther Methods Clin Dev. 17:478. PubMed
  104. Lindsay CD, et al. 2019. Acta Biomater. 95:225. PubMed
  105. Mao X, et al. 2019. Stem Cell Reports. 13:747. PubMed
  106. Saito K, et al. 2019. Cell Rep. 29:1555. PubMed
  107. Komabayashi-Suzuki M, et al. 2019. Cell Rep. 29:1113. PubMed
  108. Li L, et al. 2019. Cell Rep. 28:698. PubMed
  109. Yin WC, et al. 2019. Dev Cell. 48:167. PubMed
  110. Gao ML, et al. 2020. Front Cell Dev Biol. 8:128. PubMed
  111. Bershteyn M, et al. 2017. Cell Stem Cell. 20:435. PubMed
  112. Shu P, et al. 2019. J Biol Chem. 294:3444. PubMed
  113. Ding W, et al. 2019. J Neurosci. 39:1994. PubMed
  114. Ramzy A, et al. 2018. Endocrinology. 159:83. PubMed
  115. Omer Javed A, et al. 2018. Cell Rep. 25:368. PubMed
  116. Cheng S, et al. 2019. J Neurosci. 39:2195. PubMed
  117. Hasenpusch–Theil K, et al. 2020. eLife. 9:e58162. PubMed
  118. Ramme AP, et al. 2020. Stem Cell Research. 41:101615.. PubMed
  119. Lee EJ, et al. 2020. Cell Reports. 28(3):712-722.e3.. PubMed
  120. Roy A, et al. 2020. Acta Neuropathologica Communications. 8(1):54.. PubMed
  121. Selvadurai HJ, et al. 2020. Cell Reports. 31(2):107511.. PubMed
  122. Singer RA, et al. 2020. Cell Metabolism. 30(6):1091-1106. PubMed
  123. Tomita H, et al. 2020. Cell Reports. 30(1):215-228.e5.. PubMed
  124. Bendriem RM, et al. 2020. eLife. 8:e49376.. PubMed
  125. Yan P, et al. 2020. Cell Rep. 32:107870. PubMed
  126. Shao W, et al. 2020. Nature. 580:106. PubMed
  127. Yao H, et al. 2020. Sci Rep. 10:17445. PubMed
  128. Small K, et al. 2015. Ophthalmology. 13: 681-685. PubMed
  129. Ahmad Z, et al. 2015. PLoS One. 10: 0144597. PubMed
  130. Verheyen A, et al. 2015. PLoS One. 10: 0146127. PubMed
  131. Bandah D, et al. 2007. Invest Ophthalmol Vis Sci. 48:2503-2509. PubMed
  132. Tang K, et al. 2012. Development. 139:1630-1639. PubMed
  133. Delépine C, et al. 2016. Hum Mol Genet. 25: 146 - 157. PubMed
  134. Bando Y, et al. 2016. Cereb Cortex. 26: 106 - 117. PubMed
  135. Pataskar A, et al. 2016. EMBO J. 35: 24 - 45. PubMed
  136. Martínez-Cerdeño V, et al. 2016. Cereb Cortex. 26: 374 - 383. PubMed
  137. Conrad E, et al. 2016. Am J Physiol Endocrinol Metab. 310: E91 - E102. PubMed
  138. Radonjić N, et al. 2016. Cereb Cortex. 26: 131 - 143. PubMed
  139. Taverna E, et al. 2016. Sci Rep. 6:21206. PubMed
  140. Sancho-Martinez I, et al. 2016. Nat Commun. 7:10743. PubMed
  141. Wang W, et al. 2016. Nat Commun. 7:10936. PubMed
  142. Lin H, et al. 2016. Nature. 531:323-328. PubMed
  143. Xu J, et al. 2016. Sci Transl Med. 8: 333ra48. PubMed
  144. Otani T, et al. 2016. Cell Stem Cell. 18: 467-480. PubMed
  145. Paquet D, et al. 2016. Nature. 533: 125-129. PubMed
  146. Okamoto M, et al. 2016. Nat Commun. 7: 11349. PubMed
  147. Wang L, Hou S, Han Y 2016. Nat Neurosci. 19: 888-896. PubMed
  148. Cugola F, et al. 2016. Nature. 534: 267-271. PubMed
  149. Takeo Y, et al. 2016. Sci Rep. 6: 25180. PubMed
  150. He S, et al. 2016. Development. 143: 1937 - 1947. PubMed
  151. Anda F, et al. 2016. Nat Neurosci. 10.1038/nn.4328. PubMed
  152. Moura D, et al. 2016. Sci Rep. 6:28532. PubMed
  153. Plaisted W, et al. 2016. PLoS One. 11: 0157620. PubMed
  154. Toda T, et al. 2016. Sci Rep. 6:29578. PubMed
  155. Abdullah A, et al. 2016. Stem Cell Reports. 7:69-79. PubMed
  156. Feng J, et al. 2016. Cereb Cortex. 26: 3323 - 3334. PubMed
  157. Wiley L, et al. 2016. Sci Rep. 6:30742. PubMed
  158. Bonney S, et al. 2016. J Neurosci. 36: 7786 - 7801. PubMed
  159. Tian E, et al. 2016. Cell Rep. 16: 781-792. PubMed
  160. Hickmott J, et al. 2016. Mol Ther Methods Clin Dev. 3:16051. PubMed
  161. Gey M, et al. 2016. J Neurosci. 36: 9057 - 9069. PubMed
  162. Garreta E, et al. 2016. Biomaterials. 98:64-78. PubMed
  163. Tachibana N, et al. 2016. J Neurosci. 36: 9454 - 9471. PubMed
  164. Broix L, et al. 2016. Nat Genet. 48:1349-1358. PubMed
  165. Pei S, et al. 2016. Sci Rep. 6:33822. PubMed
  166. Zhu L, et al. 2016. J Cell Biol. 215: 187 - 202. PubMed
  167. Simonin Y, et al. 2016. EBioMedicine. 12:161-169. PubMed
  168. M Rodriguez, S Noctor, E Muñoz 2016. PLoS One. 11:e0167063. PubMed
  169. Lajko M, et al. 2016. PLoS One. 11:e0166886. PubMed
  170. Damiani D, et al. 2016. Nat Commun. 7:13509. PubMed
  171. C Tao, X Zhang, 2016. Cell Rep. 17:1832-1844. PubMed
  172. Retallack H, et al. 2016. Proc Natl Acad Sci U S A. 113(50):14408-14413. PubMed
  173. Harkin L, et al. 2016. Cereb Cortex. 10.1093/cercor/bhw394. PubMed
  174. Boland M, et al. 2017. Brain. 10.1093/brain/aww357. PubMed
  175. Breuss M, et al. 2017. Hum Mol Genet. 10.1093/hmg/ddw383. PubMed
  176. Subramanian L, et al. 2017. Nat Commun. 8:14167. PubMed
  177. Lardelli R, et al. 2017. Nat Genet. 10.1038/ng.3762. PubMed
  178. Ren R, et al. 2017. Cell Res. 10.1038/cr.2017.18. PubMed
  179. Miyashita H, et al. 2017. Sci Rep. 7:43557. PubMed
  180. Hayashi R, et al. 2017. Nat Protoc. 10.1038/nprot.2017.007. PubMed
  181. Tsai MH, et al. 2020. Acta Neuropathol Commun. 0.406944444. PubMed
  182. Ahn LY, et al. 2021. J Neurosci Res. 99:110. PubMed
  183. Ucuncu E, et al. 2020. Nat Commun. 4.685416667. PubMed
  184. Jeong D, et al. 2020. Cell Rep. 33:108257. PubMed
  185. Li Z, et al. 2020. Emerg Microbes Infect. 2.044444444. PubMed
  186. Kim HM, et al. 2020. Cell Prolif. :e12965. PubMed
  187. de Leeuw VC, et al. 2020. Cell Reprogram. 1.125. PubMed
  188. Birkhoff JC, et al. 2020. Hum Mol Genet. 29:2535. PubMed
  189. Pereiro X, et al. 2020. Cells. 9:00. PubMed
  190. Quintana-Urzainqui I, et al. 2020. Development. 147:00:00. PubMed
  191. Gregory JA, et al. 2020. Cells. 9:00. PubMed
  192. Xiao D, et al. 2020. Sci Adv. 6:eaaz5858. PubMed
  193. Chui A, et al. 2020. Development. 147:00:00. PubMed
  194. Bosze B, et al. 2020. J Neurosci. 40:1501. PubMed
  195. Li M, et al. 2021. Signal Transduct Target Ther. 6:05. PubMed
  196. Eze UC, et al. 2021. Nature Neuroscience. 24(4):584-594. PubMed
  197. Schinzel F, et al. 2021. Journal of Comparative Neurology. 529(11):3032-3045. PubMed
  198. Yu Q, et al. 2021. eLife. 10:00. PubMed
  199. Patmore DM, et al. 2020. Developmental Cell. 54(4):455-470.e5. PubMed
  200. Cederquist GY, et al. 2020. Cell Stem Cell. 27(1):35-49.e6. PubMed
  201. Somatilaka BN, et al. 2020. Developmental Cell. 54(6):710-726.e8. PubMed
  202. Zhang L, et al. 2020. Cell Stem Cell. 27(5):784-797.e11. PubMed
  203. Gao X, et al. 2020. Stem Cell Research. 48:101986. PubMed
  204. Chai G, et al. 2020. Neuron. 109(2):241-256.e9. PubMed
  205. Arber C, et al. 2021. Cell Reports. 34(2):108615. PubMed
  206. Chen M, et al. 2021. Stem Cell Research. 51:102166. PubMed
  207. Kim TW, et al. 2021. Cell Stem Cell. 28(2):343-355.e5. PubMed
  208. Kweon H, et al. 2021. Cell Reports. 34(8):108780. PubMed
  209. Haag D, et al. 2021. Cancer Cell. 39(3):407-422.e13. PubMed
  210. Schmid B, et al. 2021. Stem Cell Research. 52:102180. PubMed
  211. Merkert S, et al. 2021. Stem Cell Research. 52:102208. PubMed
  212. Sun X, et al. 2021. Stem Cell Research. 52:102230. PubMed
  213. Gao X, et al. 2021. Stem Cell Research. 53:102271. PubMed
  214. Bannier-Hlaout M, et al. 2021. Cell Stem Cell. 28(7):1221-1232.e7. PubMed
  215. Ma L, et al. 2021. Stem Cell Research. 53:102305. PubMed
  216. Li N, et al. 2021. Stem Cell Research. 53:102322. PubMed
  217. Ramme AP, et al. 2021. Stem Cell Research. 53:102327. PubMed
  218. Jia N, et al. 2021. Stem Cell Research. 53:102367. PubMed
  219. Li J, et al. 2021. Stem Cell Research. 53:102376. PubMed
  220. Nakashima H, et al. 2021. Cell Reports. 35(7):109124. PubMed
  221. Gao X, et al. 2021. Stem Cell Research. 53:102388. PubMed
  222. Padmanabhan Nair V, et al. 2021. Cell Stem Cell. . PubMed
  223. Martens YA, et al. 2021. STAR Protocols. 2(2):100571. PubMed
RRID
AB_2749901 (BioLegend Cat. No. 901302)
AB_2565003 (BioLegend Cat. No. 901301)

Antigen Details

Cell Type
Neural Stem Cells
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers, Signal Transduction, Stem Cells, Synaptic Biology, Transcription Factors
Molecular Family
Nuclear Markers
Gene ID
5080 View all products for this Gene ID 18508 View all products for this Gene ID 25509 View all products for this Gene ID
UniProt
View information about Pax-6 on UniProt.org

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For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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